Chelsea boss Maurizio Sarri makes just one change to the team that drew 1-1 with Liverpool last weekend with Ross Barkley replacing Mateo Kovacic in the starting XI.
Despite his impressive display in the 1-0 Europa League win over Vidi on Thursday, Chelsea midfielder Ruben Loftus-Cheek fails to make the bench today.
Here are the lineups for both teams
Southampton XI: McCarthy, Cedric, Yoshida, Bednarek, Hoedt, Bertrand (c), Hojbjerg, Lemina, Redmond, Gabbiadini, Ings.
Subs: Gunn, Vestergaard, Davis, Romeu, Targett, Long, Austin.
Chelsea XI: Arrizabalaga, Azpilicueta (c), Luiz, Rudiger, Alonso, Jorginho, Kante, Barkley, Willian, Hazard, Giroud.
Subs: Caballero, Morata, Cahill, Zappacosta, Fabregas, Kovacic, Pedro
Come on Chelsea!!!