Chelsea have reached the quarter-finals of the Europa League, where they will take on Czech Republic side Slavia Prague.
Luiz has enjoyed European success in his first stint at the club, and the Brazilian centre-half won both the Champions League and Europa League in back-to-back years as a Chelsea player.
The Europa League presents Chelsea’s best chance of reaching the Champions League next season, with the Blues currently sixth on the Premier League table with eight games left to play.
Although Chelsea are the favourites to win the Europa League, Luiz has now advised his teammates to be ready for anything, saying that winning a tournament never comes easy.
“To understand we have to be ready for every single moment,” Luiz told the official Chelsea website.
“Bad moments can arrive, emotional moments can arrive, hard moments can arrive, and we have to be ready for that. To win a tournament is not just flowers.
“I have learned a lot in my career, and football is nice because there is always something new, and you also have to be ready for that!”
Besides Gary Cahill who has been ousted from the first team by Maurizio Sarri, Luiz is the only surviving Chelsea player from the team that won the Champions League in 2012, defeating Bayern Munich on penalties at the Alianz Arena.
A penalty shoot-out success over Bayern Munich at the Allianz Arena was then followed by another triumph 12 months later, as Chelsea defeated Benfica 2-1 to win the Europa League.
Chelsea will return to European action against Slavia on April 11.