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This weekend’s biggest clash in the Premier League is the game between Manchester City and Chelsea at the Etihad Stadium.

Chelsea will come back from the international break with this big game waiting for the Blues, and the odds are against Chelsea going into this game.

Last season’s 6-0 defeat at the Etihad is still fresh in mind, and the bookmakers are again favouring City for this one.

In his predictions for this weekend, Michael Owen has backed City to take all three points in this clash.

Owen told BetVictor: “The game of the weekend is at the Etihad and champions Manchester City will leapfrog Chelsea in the table if they take all three points

“City won the corresponding game 6-0 last season but Chelsea did win the reverse fixture at Stamford Bridge earlier in the season and only penalties were able to split the sides at Wembley in the League Cup Final back in February.

“After their defeat at Anfield in their previous game City cannot afford to drop points, especially at the Etihad, if they are to put pressure on Liverpool in their quest for a hat-trick of titles.

“Chelsea have improved under Frank Lampard and their exciting young side are confident and talented. But beware a wounded Pep Guardiola and his side – it will have been a long international break for the City boss.”