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Chelsea boss Frank Lampard has gone for a different system after losing four of their his five league matches and also after being unable to beat any of the top six teams so far.
The Chelsea boss has gone for a more compact three at the back system, while Marcos Alonso is also back in the team.
Meanwhile, Jose Mourinho’s starting line-up has remained unchanged from his side that defeated Wolves last time out.
Spurs starting XI (4-2-3-1): Gazzaniga; Aurier, Sanchez, Alderweireld, Vertonghen; Sissoko, Dier; Lucas Moura, Alli, Son; Kane.
Substitutes: Vorm, Rose, Foyth, Winks, Lo Celso, Eriksen, Ndombele.
Chelsea starting XI (3-4-2-1): Arrizabalaga; Zouma, Rudiger, Tomori; Azpilicueta, Kante, Kovacic, Alonso; Willian, Mount; Abraham.
Substitutes: Caballero, Christiansen, James, Pulisic, Jorginho, Hudson-Odoi, Batshuayi.
Referee Anthony Taylor.