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Christian Pulisic started and scored against Real Madrid in the first leg in Spain last week but was named among the subs for the second-leg at Stamford Bridge on Wednesday night.
Chelsea boss Thomas Tuchel opted to start Kai Havertz ahead of Pulisic.
Tuchel suggested Havertz’s height was a factor in picking the German over Pulisic in his starting XI against Real Madrid.
“Christian got a bad message today unfortunately, but I am pretty sure we need more than 11 players to sneak through today and it is good to have Christian from the bench,” Tuchel told BT Sport.
“Kai gives us a little bit of height against the set-pieces and maybe in fast attacks can keep the ball.”