Chelsea boss Thomas Tuchel has made six changes to the team that played out a 2-2 draw with Liverpool in the Premier League clash on Sunday.
Kepa Arrizabalaga is in goal, Malang Sarr returns to the squad, as well as Jorginho, Saul Niguez, Hakim Ziyech and Romelu Lukaku.
See the Chelsea squad below
Chelsea starting XI: Kepa, Azpilicueta (c), Rudiger, Sarr, Alonso, Mount, Jorginho, Saul, Ziyech, Lukaku, Havertz
Subs: Bettinelli, Hall, Kovacic, Loftus-Cheek, Barkley, Hudson-Odoi, Pulisic, Vale, Wendy
Tottenham Hotspur starting XI: Lloris, Tanganga, Sanchez, Davies, Emerson, Hojbjerg, Skipp, Doherty, Lucas Moura, Kane, Son.
Subs: Reguilon, Winks, Gil Salvatierra, Rodon, Lo Celso, Alli, Gollini, Ndombele, Austin.